After installing Windows 8, I was setting up the new OS for work, play and development. Almost everything went without any issues, except - when I tried connecting through Cisco VPN, I got an error message :
"Reason 442 : Failed to enable Virtual Adapter"
Following are steps I took to solve the issue, and hope it works for you as well.
Warning: The solution involves editing windows 8 registry. Done the wrong way, editing the registry may cause your Win-8 to become unstable, and you may need to re-install windows. Proceed with caution, and only if you know what you are doing.
1) On the "Run" dialog (Windows Key + R), type "regedit".
2) Go to HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\CVirtA
3) Double Click on "Display Name" string to edit it, and change it to "Cisco Systems VPN Adapter for 64-bit Windows"
4) Exit Regedit; Start Cisco VPN, and try to connect. It should work now!.
Good Luck!
References:
http://www.bidn.com/blogs/BradSchacht/ssis/3103/cisco-vpn-client-5-on-windows-8